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Title:
カテコールで官能化された磁性ナノ粒子、その生成および使用
Document Type and Number:
Japanese Patent JP6590809
Kind Code:
B2
Abstract:
There are described magnetic nanoparticles the surface of which is functionalized with catechol and constructs comprising a plurality of said nanoparticles encapsulated in a biocompatible polymer matrix, wherein a molecule with therapeutic action is optionally dispersed, said polymer matrix optionally being in turn further functionalized; there are further described cells of the immune system incorporating said polymeric constructs giving rise to their engineering.

Inventors:
Bardi Giovanni
Lavagli Costanza
Comes Francini Mauro
Delois Mario Mirco
Benagiano Marisa
Bittossi Marco
Application Number:
JP2016542675A
Publication Date:
October 16, 2019
Filing Date:
January 07, 2015
Export Citation:
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Assignee:
Cororovia italy societa peracioni
International Classes:
A61K33/26; A61K9/10; A61K31/07; A61K31/616; A61K33/242; A61K35/15; A61K35/17; A61K38/19; A61K39/395; A61K47/34; A61K47/69; A61K49/18; A61P1/16; A61P9/00; A61P25/28; A61P31/00; A61P35/00; A61P37/06
Domestic Patent References:
JP2012111694A
Foreign References:
WO2011147926A1
Other References:
SOUDABEH DAVARAN ET AL: "Preparation and in vitro evaluation of doxorubicin-loaded Fe3O4 magnetic nanoparticles modified with biocompatible copolymers", INTERNATIONAL JOURNAL OF NANOMEDICINE, 1 February 2012 (2012-02-01), page 511, XP055118165, DOI: 10.2147/IJN.S24326
Attorney, Agent or Firm:
Masao Sekiguchi
Takamasa Nakano