Title:
フッソ含有重水素化ジフェニル尿素の製造方法
Document Type and Number:
Japanese Patent JP2013522244
Kind Code:
A
Abstract:
Methods and processes for preparation and production of deuterated É-diphenylurea are disclosed. Especially, a kind of deuterated É-diphenylurea compounds which can inhibit phosphokinase and the preparation method of N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N- d3 -methylcarbamoyl)-4-pridinylox y)phenyl)urea are disclosed. The said deuterated diphenylurea compounds can be used for treating or preventing tumors and relative diseases.
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Inventors:
Fan Mamoru East
High and low
Taku Akatsuki Shun
High and low
Taku Akatsuki Shun
Application Number:
JP2012557395A
Publication Date:
June 13, 2013
Filing Date:
March 17, 2011
Export Citation:
Assignee:
Su State Sawa Jin Biological Drug Co., Ltd.
International Classes:
C07D213/81; A61K31/44; A61P35/00; C07C273/18; C07C275/34; C07B59/00
Domestic Patent References:
| JP2006528196A | 2006-12-14 | |||
| JP2006528196A | 2006-12-14 |
Foreign References:
| US20090069388A1 | 2009-03-12 | |||
| WO2009054004A2 | 2009-04-30 | |||
| WO2009034308A2 | 2009-03-19 | |||
| WO2008089388A2 | 2008-07-24 | |||
| WO2008089389A2 | 2008-07-24 | |||
| WO2010019701A2 | 2010-02-18 | |||
| WO2010144499A2 | 2010-12-16 | |||
| US20090069388A1 | 2009-03-12 | |||
| WO2009054004A2 | 2009-04-30 | |||
| WO2009034308A2 | 2009-03-19 | |||
| WO2008089388A2 | 2008-07-24 | |||
| WO2008089389A2 | 2008-07-24 |
Attorney, Agent or Firm:
Nobuo Kono
Hideno Kono
Hideno Kono