Title:
親水性ポリ−Ｎ−ビニルピロリドンの製造方法およびその使用
Document Type and Number:
Japanese Patent JP5739413
Kind Code:
B2
Abstract:
The present invention relates to a process for the production of the largest possible spherical, monodisperse polyvinylpyrrolidone (PVP) seed particles in the micron range by dispersion polymerisation. The particles obtained in this way represent novel starting materials for the production of macroporous polymer particles, which can in turn be employed in preparative and analytical chromatography for protein preparation. They can also be employed as base material for further reactions. The novel process for the polymerisation of N-vinylpyrrolidone, which is inexpensive to carry out, gives particles having optimised quantities, such as monodispersity, sphericity and particle diameter, which can be employed in further reactions and have advantageous, in particular improved, properties for use in chromatographic separation methods.
Inventors:
Janck, Matthias
Scheid, daniel
Scheid, daniel
Application Number:
JP2012508932A
Publication Date:
June 24, 2015
Filing Date:
April 27, 2010
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C08F2/06; C08F26/10; G01N30/88
Domestic Patent References:
| JP46016890B1 | ||||
| JP3170504A | ||||
| JP62100508A | ||||
| JP51082387A | ||||
| JP10298245A | ||||
| JP64026617A | ||||
| JP2000191818A |
Foreign References:
| US5073614 | ||||
| US5362815 |
Attorney, Agent or Firm:
Kiyoji Kuzuwa