Title:
リン酸オセルタミビルの製造方法及び中間体化合物
Document Type and Number:
Japanese Patent JP5567477
Kind Code:
B2
Abstract:
Disclosed are a process suited to large scale synthesis with high yield for producing oseltamivir phosphate, in which a preparation of oseltamivir phosphate which is highly safe as a pharmaceutical product can be produced, and an intermediate compound for producing oseltamivir phosphate. In this production process, an intermediate compound represented by general formula (V) is synthesized by employing Michael reaction/Michael reaction/Horner-Wadsworth-Emmons reaction, and oseltamivir phosphate is produced by converting the substituent groups in this intermediate compound.
Inventors:
Yujiro Hayashi
Ishikawa Hayato
Ishikawa Hayato
Application Number:
JP2010514536A
Publication Date:
August 06, 2014
Filing Date:
May 28, 2009
Export Citation:
Assignee:
Sumitomo Chemical Co., Ltd.
Yujiro Hayashi
Ishikawa Hayato
Yujiro Hayashi
Ishikawa Hayato
International Classes:
C07C231/08; C07C47/198; C07C201/12; C07C205/54; C07C205/55; C07C227/16; C07C229/48; C07C231/10; C07C233/52; C07C233/91; C07C247/22; C07C263/12; C07C265/10; C07C319/18; C07C319/20; C07C323/61; C07D209/48
Domestic Patent References:
| JP2008081489A | 2008-04-10 | |||
| JP2008081489A | 2008-04-10 |
Foreign References:
| WO2002040019A1 | 2002-05-23 | |||
| WO2002040019A1 | 2002-05-23 |
Other References:
JPN6013053865; 有機合成シンポジウム講演要旨集 Ｖｏｌ．９４ｔｈ, ｐ．２６-２７ （２００８）．
JPN6013053865; 有機合成シンポジウム講演要旨集 Ｖｏｌ．９４ｔｈ, ｐ．２６-２７ （２００８）．
JPN6013053865; 有機合成シンポジウム講演要旨集 Ｖｏｌ．９４ｔｈ, ｐ．２６-２７ （２００８）．
Attorney, Agent or Firm:
Masayuki Masabayashi