Title:
(2R,3S)-3-フェニルイソセリンメチルエステル酢酸塩の製造方法
Document Type and Number:
Japanese Patent JP2010519262
Kind Code:
A
Abstract:
A process for the enantioselective preparation of (2 R ,3 S )-3-phenylisoserine methyl ester acetate salt of formula (I)
which is an useful building block for the synthesis of taxane derivatives. The process involves the resolution of racemic threo-phenylisoserine amide and its conversion into (I).
Inventors:
Chicheri, Daniele
Gabbetta, Bruno
Vignola, Nikola
Mitter, Frieder
Weber, Beat Ther
Gabbetta, Bruno
Vignola, Nikola
Mitter, Frieder
Weber, Beat Ther
Application Number:
JP2009550666A
Publication Date:
June 03, 2010
Filing Date:
February 11, 2008
Export Citation:
Assignee:
Indena Sochieta Pell Ationi
International Classes:
C07C227/18; C07B53/00; C07B57/00; C07C227/42; C07C229/34; C07C231/12; C07C231/20; C07C237/20
Domestic Patent References:
JP2005500322A | 2005-01-06 | |||
JPH02167253A | 1990-06-27 | |||
JPH06271512A | 1994-09-27 | |||
JP2004531498A | 2004-10-14 | |||
JP2009114065A | 2009-05-28 |
Foreign References:
WO2004063141A1 | 2004-07-29 | |||
US6025516A | 2000-02-15 |
Other References:
TETRAHEDRON: ASYMMETRY, vol. 11, JPN7013000156, 2000, pages 2117 - 2123, ISSN: 0002435712
Attorney, Agent or Firm:
Hajime Tsukuni
Koshiro Tsukuda
Fusayuki Saito
Koshiro Tsukuda
Fusayuki Saito