Title:
ロスバスタチンカリウムの製造方法
Document Type and Number:
Japanese Patent JP2009530232
Kind Code:
A
Abstract:
A process of manufacturing of Rosuvastatin Potassium of formula (I) is disclosed. The process comprises the steps of (a) treating Rosuvastatin protected compound of formula (II) wherein R1 and R2 are same or different having C1-C4 carbon atom or hydrogen or R1 and R2 can combine together to afford a cyclic structure comprising a junction atom as carbon or metal atom such as Si (silicon); with an inorganic base of the kind such as herein described having potassium as cation in a suitable solvent to form Rosuvastatin potassium; (b) isolating Rosuvastatin potassium.
Inventors:
Dimant Jasbhai Patel
Rajiv Kumar
Virendra Kumar Agawar
Rajiv Kumar
Virendra Kumar Agawar
Application Number:
JP2008551959A
Publication Date:
August 27, 2009
Filing Date:
January 25, 2007
Export Citation:
Assignee:
Cadilla Healthcare Limited
International Classes:
C07D239/42
Domestic Patent References:
| JPH05178841A | 1993-07-20 |
Attorney, Agent or Firm:
Masatake Shiga
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro
Takashi Watanabe
Yasuhiko Murayama
Shinya Mitsuhiro