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Title:
A manufacturing method of the substrate which has a hydrophilic layer
Document Type and Number:
Japanese Patent JP6102458
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To provide a method for stably introducing a high-quality hydrophilic layer capable of sufficiently inhibiting nonspecific adsorption of a bio-related substance such as protein into a plastic surface of a substrate.SOLUTION: A production method of a substrate having a hydrophilic layer on a surface thereof is provided, which includes: a substrate preparation step of preparing a substrate having a plastic surface; a plasma treatment step 1 of exposing the plastic surface of the substrate to plasma containing rare gas; a plasma treatment step 2 of exposing the plastic surface of the substrate to plasma containing fluorocarbon gas; a primer layer formation step of forming a primer layer containing polysiloxane by polymerizing a silanol compound having an organic group that contains a carbon atom directly bonded to a silicon atom and has a functional group, on the surface of the substrate exposed to plasma; and a hydrophilic layer formation step of linking the primer layer with a hydrophilic polymer via a covalent bond by the reaction of the functional group on a side chain of the polysiloxane with a functional group of the hydrophilic polymer.

Inventors:
Yuichi Tanaka
Application Number:
JP2013088516A
Publication Date:
March 29, 2017
Filing Date:
April 19, 2013
Export Citation:
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Assignee:
Dai Nippon Printing Co.,Ltd.
International Classes:
B32B27/00; B32B27/30; B32B38/00; C08J7/00; C08J7/04
Domestic Patent References:
JP2013011480A
JP2013049819A
JP4022628A
JP59140233A
JP2001255625A
JP2013237812A
Foreign References:
WO2010131372A1
Attorney, Agent or Firm:
Yusuke Hiraki
Satoshi Fujita
Ai Fujii