Title:
テトラヒドロイソキノリンの製造方法
Document Type and Number:
Japanese Patent JP2011524346
Kind Code:
A
Abstract:
Disclosed are processes for preparing tetrahydroisoquinolines, intermediates useful in the preparation of tetrahydroisoquinolines, processes for preparing such intermediates, and a crystalline form of 6-[(4S)-2-methyl-4-(naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine. Also disclosed are pharmaceutical compositions comprising tetrahydroisoquinolines, methods of using tetrahydroisoquinolines in the treatment of depression and other conditions and methods for obtaining the crystalline form.
Inventors:
Paul Robben
Lurin Chao
Bay One
Chen Bang-chi
Xuan Liu
Hu Min
You-Lin Allen Yang
Matthew Isherwood
Rasidur Amin
Kui Wenge
Lurin Chao
Bay One
Chen Bang-chi
Xuan Liu
Hu Min
You-Lin Allen Yang
Matthew Isherwood
Rasidur Amin
Kui Wenge
Application Number:
JP2011512646A
Publication Date:
September 01, 2011
Filing Date:
June 04, 2009
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
Albany Molecular Research, Inc.
Albany Molecular Research, Inc.
International Classes:
C07C225/16; C07C215/30; C07C217/58; C07C221/00; C07D217/04; C07D401/04; C07F5/02; A61K31/50; A61P25/24
Domestic Patent References:
| JP2008506711A | 2008-03-06 |
Attorney, Agent or Firm:
Kyousei Tamura
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka
Samejima Mutsumi
Nagatoshi Shinagawa
Yasushi Morimoto
Shinichiro Yamanaka