Title:
A manufacturing process of cyclohepten
Document Type and Number:
Japanese Patent JP5916855
Kind Code:
B2
Abstract:
The present invention provides a process for preparing cycloheptene and derivatives thereof by ring-closure metathesis of asymmetric 1,8-dienes whose C-C double bond in position 8 is not terminal. Cycloheptene and also its derivatives cycloheptanone, cycloheptylamine, cycloheptanecarbaldehyde, cycloheptanecarboxylic acid and cycloheptanecarbonyl chloride, and also their derivatives, are important synthetic building blocks for active compounds. The ring-closure metathesis is performed preferably as a reactive distillation. The asymmetric 1,8-dienes for the ring-closure metathesis can be obtained by catalytic decarbonylation or oxidative decarboxylation of the corresponding unsaturated carboxylic acids and/or carboxylic acid derivatives.
Inventors:
Joaquin Enrique Teres
Michael linbach
Richard Dane
Stephan doyer line
Manuel Danz
Michael linbach
Richard Dane
Stephan doyer line
Manuel Danz
Application Number:
JP2014519497A
Publication Date:
May 11, 2016
Filing Date:
July 03, 2012
Export Citation:
Assignee:
BASF SE
International Classes:
C07C6/04; B01J31/22; B01J31/24; C07C13/24
Domestic Patent References:
| JP2011516556A | ||||
| JP2009533215A | ||||
| JP47012345B1 |
Foreign References:
| US20040087438 | ||||
| US5077447 |
Other References:
I. W. ASHWORTH,ON THE RELATIONSHIP BETWEEN STRUCTURE AND REACTION RATE IN OLEFIN RING-CLOSING METATHESIS,CHEMICAL COMMUNICATIONS,2010年,V46,P7145-7147
DENMARK S. E.,SEQUENTIAL RING-CLOSING METATHESIS/PD-CATALYZED, SI-ASSISTED CROSS-COUPLING REACTIONS: 以下備考,TETRAHEDRON,NL,ELSEVIER SCIENCE PUBLISHERS,2004年10月18日,V60 N43,P9695-9708,GENERAL SYNTHESIS OF HIGHLY SUBSTITUTED UNSATURATED ALCOHOLS AND MEDIUM-SIZED RINGS 以下省略
V. S. C. YEH,SYNTHESIS AND STRUCTURAL ACTIVITY RELATIONSHIP OF 11BETA-HSD1 INHIBITORS 以下備考,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,英国,ELSEVIER SCIENCE LTD.,2006年,V16,P5408-5413,WITH NOVEL ADAMANTANE REPLACEMENTS
A. BEN-ASULY,A THERMALLY SWITCHABLE LATENT RUTHENIUM OLEFIN METATHESIS CATALYST,ORGANOMETALLICS,ACS AMERICAN CHEMICAL SOCIETY,2008年,V27,P811-813
DENMARK S. E.,SEQUENTIAL RING-CLOSING METATHESIS/PD-CATALYZED, SI-ASSISTED CROSS-COUPLING REACTIONS: 以下備考,TETRAHEDRON,NL,ELSEVIER SCIENCE PUBLISHERS,2004年10月18日,V60 N43,P9695-9708,GENERAL SYNTHESIS OF HIGHLY SUBSTITUTED UNSATURATED ALCOHOLS AND MEDIUM-SIZED RINGS 以下省略
V. S. C. YEH,SYNTHESIS AND STRUCTURAL ACTIVITY RELATIONSHIP OF 11BETA-HSD1 INHIBITORS 以下備考,BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,英国,ELSEVIER SCIENCE LTD.,2006年,V16,P5408-5413,WITH NOVEL ADAMANTANE REPLACEMENTS
A. BEN-ASULY,A THERMALLY SWITCHABLE LATENT RUTHENIUM OLEFIN METATHESIS CATALYST,ORGANOMETALLICS,ACS AMERICAN CHEMICAL SOCIETY,2008年,V27,P811-813
Attorney, Agent or Firm:
Einzel Felix-Reinhard
Takuya Kuno
Takuya Kuno