Title:
デプシペプチド誘導体の製造法およびその新規中間体
Document Type and Number:
Japanese Patent JP4035852
Kind Code:
B2
Abstract:
An industrially excellent alternative process for producing cyclodepsipeptide derivatives, as represented in formula (1), having an excellent vermicidal activity as an animal and human anthelmintic, wherein R1 represents hydrogen or a hydroxyl-protective group; R2 represents a carboxyl group optionally protected; R3, R4, R7 and R8 represent each a lower alkyl, aryl or (un)substituted aralkyl; and R5, R6, R9 and R10 represent each a lower alkyl.
Inventors:
Ryo Yamanishi
Ogaki Masaru
Ogaki Masaru
Application Number:
JP51737098A
Publication Date:
January 23, 2008
Filing Date:
September 24, 1997
Export Citation:
Assignee:
Astellas Pharma Inc.
International Classes:
C07C235/12; C07D273/00; C07D295/155
Domestic Patent References:
| JP6340694A | ||||
| JP6340695A |
Foreign References:
| WO1993019053A1 |
Other References:
Hiroki Sane, et.al., ”Isolation, Structure, and Synthesis of Dolastatin D, a Cytotoxic Cyclic Depsipeptide from the Sea Hare Dolabella auricularia”, Tetrahedron Letters, 英国, 1993年, Vol.34, No.52, p.8449-8452
Attorney, Agent or Firm:
Hamai Kosuke