Title:
【発明の名称】糖尿病、高脂血症、高コレステロール血症、およびアテローム性動脈硬化症の治療のための材料と方法
Document Type and Number:
Japanese Patent JP2003531200
Kind Code:
A
Abstract:
The subject invention provides pharmaceutical compounds useful in the treatment of Type II diabetes. These compounds are advantageous because they are readily metabolized by the metabolic drug detoxification systems. Particularly, thiazolidinedione analogs that have been designed to include esters within the structure of the compounds are provided. This invention is also drawn to methods of treating disorders, such as diabetes, comprising the administration of therapeutically effective compositions comprising compounds that have been designed to be metabolized by serum or intracellular hydrolases and esterases. Pharmaceutical compositions of the ester-containing thiazolidinedione analogs are also taught.
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Inventors:
Doraz gala pascal
Mirinel Peter G.
Pfister Jurguar.
Mirinel Peter G.
Pfister Jurguar.
Application Number:
JP2001578420A
Publication Date:
October 21, 2003
Filing Date:
April 24, 2001
Export Citation:
Assignee:
Alix Therapeutics
International Classes:
A61K31/426; A61K31/427; A61K31/428; A61K31/4439; A61K31/497; A61K31/569; A61P3/06; A61P3/10; A61P9/10; C07D261/12; C07D277/20; C07D277/34; C07D311/70; C07D413/04; C07D413/12; C07D417/04; C07D417/12; C07D417/14; C07J3/00; (IPC1-7): C07D277/34; A61K31/426; A61K31/427; A61K31/428; A61K31/4439; A61K31/497; A61K31/569; A61P3/06; A61P3/10; A61P9/10; C07D417/12; C07D417/14; C07J3/00
Attorney, Agent or Firm:
Shimizu Hatsushi (1 person outside)