【発明の名称】新規アクロニシン化合物、その製造方法及びそれを含有する医薬組成物

Title:

【発明の名称】新規アクロニシン化合物、その製造方法及びそれを含有する医薬組成物

Document Type and Number:

Japanese Patent JP2001526290

Kind Code:

A

Abstract:

A compound selected from those of formula (I):in which:X and Y represent hydrogen, halogen, hydroxy, mercapto, cyano, nitro, alkyl, alkoxy, trihaloalkyl, optionally substituted amino, methylenedioxy, or ethylenedioxy,R1 represents hydrogen, or alkyl,R2 represents hydrogen, hydroxy, alkyl, alkoxy, alkylcarbonyloxy, or optionally substituted ammo,R3 and R4 represent hydrogen, or alkyl,A represents -CH=CH-, or -CH(R5)-CH(R6)- wherein R5 and R6 are as defined in the description,their isomers, N-oxides, and pharmaceutically-acceptable acid or base addition salts thereof,and medicinal products containing the same which are useful in the treatment of cancer.

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Inventors:

Cook, michel
Francois, Tyucan
Michelle, Sylvie
Atasi, Gurham
Alain Pierre
Pfeiffer, Bruno
Renard, Pierre

Application Number:

JP2000525428A

Publication Date:

December 18, 2001

Filing Date:

December 18, 1998

Export Citation:

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Assignee:

Adair e Company

International Classes:

A61K31/4741; A61K31/4745; A61K31/553; A61P35/00; C07D491/04; C07D491/052; C07D491/14; C07D491/153; C07D498/14; (IPC1-7): C07D491/052; A61K31/4741; A61K31/4745; A61K31/553; A61P35/00; C07D491/14; C07D498/14

Attorney, Agent or Firm:

Hajime Tsukuni (1 person outside)

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