Title:
【発明の名称】腫瘍または白血病治療用のラブダン類を含む製薬組成物
Document Type and Number:
Japanese Patent JP2003513902
Kind Code:
A
Abstract:
The present invention relates to novel compositions based on hydrated lipidic lamellar phases or liposomal compositions, prepared by combining different lipid molecules, synthetic and/or from natural sources, said compositions comprising at least one of a) labd-13-ene-8alpha, 15-diol and/or derivatives thereof; b) labd-14-ene-8, 13-diol or derivatives thereof; c) 3beta-hydroxy-labd-14-ene-8, 13-epoxy and/or derivatives thereof, d) a plant extract containing the aforementioned labdanes or derivatives thereof. The compositions of the invention exhibit cytotoxicity against cancerous cells and are utilized for the treatment of tumors and leukemias.
Inventors:
Demezzos Constantinos
Dimas Constantinos
Angelopourou Demetra
Anastassaki Thalia
Kokinopoulos Demetrius
Dimas Constantinos
Angelopourou Demetra
Anastassaki Thalia
Kokinopoulos Demetrius
Application Number:
JP2001536116A
Publication Date:
April 15, 2003
Filing Date:
November 08, 2000
Export Citation:
Assignee:
Paen Gerorimatos Society Anonymous
International Classes:
C07D311/92; A61K9/127; A61K9/133; A61K31/047; A61K31/22; A61K31/352; A61P35/00; A61P35/02; (IPC1-7): A61K31/047; A61K9/127; A61K31/22; A61K31/352; A61P35/00; A61P35/02
Attorney, Agent or Firm:
Minoru Nakamura (9 outside)