Title:
ＡＡＶを検出するための方法
Document Type and Number:
Japanese Patent JP2019533803
Kind Code:
A
Abstract:
本明細書に提供されるのは、ウイルス粒子の血清型を決定するための方法および／またはウイルス粒子（例えば、ＡＡＶ粒子）の不均一性を決定するための方法である。他の実施形態では、本発明は、ＡＡＶ粒子の不均一性を決定する方法を提供する。一部の態様では、本発明は、カプシドタンパク質のアセチル化および／または脱アミド化を増加させることにより、改善された安定性および／または改善された形質導入効率を有するウイルス粒子（例えば、ｒＡＡＶ粒子）を提供する。
Inventors:
Xiao Yin Jin
Catherine Earl Oriodan
Lynn Liu
Kate Chan
Catherine Earl Oriodan
Lynn Liu
Kate Chan
Application Number:
JP2019508235A
Publication Date:
November 21, 2019
Filing Date:
August 14, 2017
Export Citation:
Assignee:
GENZYME CORPORATION
International Classes:
G01N33/483; A61K35/76; C07K14/015; C12N7/01; C12N15/37; G01N27/62; G01N30/72; G01N33/48
Domestic Patent References:
| JP2006510875A | 2006-03-30 |
Other References:
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Attorney, Agent or Firm:
Junji Yuda
Noriyuki Takebayashi
Noriyuki Takebayashi