Title:
A method and a device for compounding contrast media and its intermediate
Document Type and Number:
Japanese Patent JP6254126
Kind Code:
B2
Abstract:
The present invention generally relates to methods and system for the synthesis of imaging agents, and precursors thereof. The methods may exhibit improved yields and may allow for the large-scale synthesis of imaging agents, including imaging agents comprising a radioisotope (e.g., 18F). Various embodiments of the invention may be useful as sensors, diagnostic tools, and the like. In some cases, methods for evaluating perfusion, including myocardial perfusion, are provided. Synthetic methods of the invention have also been incorporated into an automated synthesis unit to prepare and purify imaging agents that comprise a radioisotope. In some embodiments, the present invention provides a novel methods and systems comprising imaging agent 1, including methods of imaging in a subject comprising administering a composition comprising imaging agent 1 to a subject by injection, infusion, or any other known method, and imaging the area of the subject wherein the event of interest is located.
Inventors:
Richard Earl Cesaty
Edward H. Cheeseman
Joel Razewatsky
Haike s radeque
James F. Kastner
Enrico Mongo
Diane Di Dunkywitz
Robert Wilburn Siegler
Mary Beth Devine
Edward H. Cheeseman
Joel Razewatsky
Haike s radeque
James F. Kastner
Enrico Mongo
Diane Di Dunkywitz
Robert Wilburn Siegler
Mary Beth Devine
Application Number:
JP2015181159A
Publication Date:
December 27, 2017
Filing Date:
September 14, 2015
Export Citation:
Assignee:
Lanseus Medical Imaging, Inc.
International Classes:
C07D237/16; A61K51/04
Domestic Patent References:
| JP2007112725A |
Foreign References:
| WO2009110984A1 | ||||
| CN101555232A | ||||
| WO2009054653A1 |
Other References:
Bioorganic & Medicinal Chemistry,2010年,18,pp.1312~1320,Available online 26 Dec.2009
Tetrahedron Letters,2007年,48,pp.3953~3957
Bioconjugate Chem.,2004年,15(1),pp.104~111
Tetrahedron Letters,2007年,48,pp.3953~3957
Bioconjugate Chem.,2004年,15(1),pp.104~111
Attorney, Agent or Firm:
Samejima Mutsumi
Yasushi Morimoto
Nobuhiko Akiyama
Yasushi Morimoto
Nobuhiko Akiyama
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