Title:
天然l-メントールを生成するための方法及び装置
Document Type and Number:
Japanese Patent JP2012517993
Kind Code:
A
Abstract:
Embodiments are provided that provide for efficient production of highly pure natural I-menthol. In some embodiments, a method for preparing natural I-menthol involves providing crude mentha oil in a crystallizer and gradually reducing the temperature of the crystallizer in a step-wise manner, thereby producing highly pure crystals in less than two weeks. The methods disclosed herein are suitable for pharmaceutical GMP.
Inventors:
Ryosuke Nagaoka
Hideaki Izumikura
Susumu Tokita
Shibata Yuri
Yoshiyuki Nagaoka
Hideaki Izumikura
Susumu Tokita
Shibata Yuri
Yoshiyuki Nagaoka
Application Number:
JP2011549696A
Publication Date:
August 09, 2012
Filing Date:
February 17, 2010
Export Citation:
Assignee:
Nagaoka Business Co., Ltd.
International Classes:
A23L27/20; C07C29/78; C07C35/12; C07B57/00
Domestic Patent References:
| JPS55111427A | 1980-08-28 | |||
| JPS4720142A | ||||
| JP2005528436A | 2005-09-22 | |||
| JPH09217084A | 1997-08-19 | |||
| JPS57200321A | 1982-12-08 | |||
| JP2008230978A | 2008-10-02 | |||
| JPS4626933B1 | 1971-08-05 | |||
| JPS55111427A | 1980-08-28 | |||
| JPS4720142A |
Attorney, Agent or Firm:
Hiroshi Maeda
Hiroshi Takeuchi
Takahisa Shimada
Yuji Takeuchi
Katsumi Imae
Kazunari Ninomiya
Tomoo Harada
Seki Kei
Yasuya Sugiura
Daisuke Kawabe
Masanori Hasegawa
Tsuguya Iwashita
Koji Fukumoto
Ryo Maeda
Mawaki Hachizo
Yukichi Matsunaga
Kenji Kawakita
Shohei Okazawa
Hiroshi Takeuchi
Takahisa Shimada
Yuji Takeuchi
Katsumi Imae
Kazunari Ninomiya
Tomoo Harada
Seki Kei
Yasuya Sugiura
Daisuke Kawabe
Masanori Hasegawa
Tsuguya Iwashita
Koji Fukumoto
Ryo Maeda
Mawaki Hachizo
Yukichi Matsunaga
Kenji Kawakita
Shohei Okazawa