Title:
不斉酸化によるモダフィニルの単一エナンチオマーのエナンチオ選択的合成方法
Document Type and Number:
Japanese Patent JP4713480
Kind Code:
B2
Abstract:
The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of : a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent ; and optionally b) isolating the obtained sulphoxide of formula (I). wherein n, Y, R1, R1a, R2 and R2a are as defined in claim 1.
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Inventors:
Leviere, Francois
Duret, Gerard
Pla, lawrence
Duret, Gerard
Pla, lawrence
Application Number:
JP2006526728A
Publication Date:
June 29, 2011
Filing Date:
September 17, 2004
Export Citation:
Assignee:
CEPHALON FRANCE
International Classes:
C07C315/02; C07C317/44; C07C319/20; C07C323/60; C07B53/00; C07B61/00
Domestic Patent References:
| JP62190160A | ||||
| JP59001459A | ||||
| JP2004509080A | ||||
| JP53121724A |
Other References:
Pure and Applied Chemistry,1985年,57(12),p.1911-1916
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazumi Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazumi Nakamura