Title:
IgG結合のための部位を同定するための方法
Document Type and Number:
Japanese Patent JP2012528601
Kind Code:
A
Abstract:
The present disclosure relates to immunoglobulins and immunoglobulin conjugates with reduced oligomerization and efficient labeling and compositions, methods of generating such immunoglobulins and immunoglobulin conjugates and methods of using such immunoglobulin conjugates particularly in the treatment and prevention of disease.
Inventors:
Chenam Setti, Naresh
Helk, Bernhard
Kaiser, Bethel
Trout, burn heart
Boinov, Bradymir
Helk, Bernhard
Kaiser, Bethel
Trout, burn heart
Boinov, Bradymir
Application Number:
JP2012514202A
Publication Date:
November 15, 2012
Filing Date:
June 04, 2010
Export Citation:
Assignee:
Novartis Age
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
MASSACHUSETTS INSTITUTE OF TECHNOLOGY
International Classes:
C12N15/09; A61K31/7088; A61K31/7105; A61K38/00; A61K39/395; A61K45/00; A61K47/42; A61K47/48; A61K48/00; A61K49/00; A61P1/02; A61P1/04; A61P1/16; A61P3/02; A61P3/06; A61P3/10; A61P3/14; A61P5/38; A61P7/00; A61P9/04; A61P9/10; A61P15/00; A61P17/00; A61P17/06; A61P17/10; A61P19/02; A61P19/08; A61P19/10; A61P25/00; A61P25/28; A61P27/02; A61P27/06; A61P29/00; A61P31/04; A61P31/12; A61P31/18; A61P35/00; A61P35/02; A61P35/04; A61P37/02; A61P37/06; A61P43/00; C07K16/00; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Domestic Patent References:
| JP2009017881A | 2009-01-29 | |||
| JP2009504164A | 2009-02-05 | |||
| JP2008516896A | 2008-05-22 |
Foreign References:
| WO2008088983A1 | 2008-07-24 |
Other References:
J. IMMUNOL. METHODS, vol. vol.332, no.1-2, JPN6014036819, 2008, pages 41 - 52, ISSN: 0003047992
NAT. BIOTECHNOL., vol. 26, no. 8, JPN6014036821, 2008, pages 925 - 932, ISSN: 0003047993
NAT. BIOTECHNOL., vol. 26, no. 8, JPN6014036821, 2008, pages 925 - 932, ISSN: 0003047993
Attorney, Agent or Firm:
Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita
Takaaki Yasumura
Natsuki Morishita