Title:
The method and intermediate for manufacturing the prostagladin which does not include an opposite-sex object
Document Type and Number:
Japanese Patent JP6013412
Kind Code:
B2
Abstract:
Novel processes for the preparation of a compound of Formula I-2 substantially free of the 5,6- trans isomer:
wherein
R 2 , R 3 and R 4 are as defined in the specification are provided. Novel intermediates for the preparations of isomer free Prostaglandins and derivatives thereof are also provided.
Inventors:
Way
Yeah, Yu Chi
Su, Min-Kwan
Khao, Rita
Yeah, Yu Chi
Su, Min-Kwan
Khao, Rita
Application Number:
JP2014164880A
Publication Date:
October 25, 2016
Filing Date:
August 13, 2014
Export Citation:
Assignee:
CHIROGATE INTERNATIONAL INC.
International Classes:
C07C405/00
Domestic Patent References:
| JP2005539014A | ||||
| JP2003517441A | ||||
| JP2012520294A | ||||
| JP2012507552A |
Foreign References:
| WO2011008756A1 | ||||
| WO2013093528A1 | ||||
| US20050209337 | ||||
| WO2012001009A1 | ||||
| US3935240 |
Other References:
Jacek G. Martynow, et al.,A New Synthetic Approach to High-Purity (15R)-Latanoprost, Wiley Online LibraryYou have full text access to this contentEuropean Journal of Organic Chemistry,2006年,Vol.2007, No.4,pp.689-703
Yasushi Matsumura, et al,,Synthesis of the highly potent prostanoid FP receptor agonist, AFP-168: a novel 15-deoxy-15,15-difluoroprostaglandin F2α derivative,Tetrahedron Letters,2004年,Volume45, Issue7,pp.1527-1529
E. J. Corey, et al.,Synthesis of novel macrocyclic lactones in the prostaglandin and polyether antibiotic series,J. Am. Chem. Soc.,1975年,Vol.97, No.3 ,pp.653-654
Gordon L. Bundy, et al.,Synthesis and biological activity of prostaglandin lactones,J. Med. Chem.,1983年,Vol.26, No.8,pp.1089-1099
Yasushi Matsumura, et al,,Synthesis of the highly potent prostanoid FP receptor agonist, AFP-168: a novel 15-deoxy-15,15-difluoroprostaglandin F2α derivative,Tetrahedron Letters,2004年,Volume45, Issue7,pp.1527-1529
E. J. Corey, et al.,Synthesis of novel macrocyclic lactones in the prostaglandin and polyether antibiotic series,J. Am. Chem. Soc.,1975年,Vol.97, No.3 ,pp.653-654
Gordon L. Bundy, et al.,Synthesis and biological activity of prostaglandin lactones,J. Med. Chem.,1983年,Vol.26, No.8,pp.1089-1099
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto
Toshio Takano
Toshio Nakajima
Masaki Murata
Hiroto Yamamoto