腫瘍サプレッサ遺伝子、並びに癌の検出、腫瘍進行のモニタおよび癌処理のための方法 - ザリージェンツオブザユニバーシティオブカリフォルニア

Title:

腫瘍サプレッサ遺伝子、並びに癌の検出、腫瘍進行のモニタおよび癌処理のための方法

Document Type and Number:

Japanese Patent JPH09511910

Kind Code:

A

Abstract:

A gene that encodes an inhibitor of CDK4 has been discovered and its genomic nucleotide sequence has been identified. Susceptibility to certain cancers has been shown to be causatively related to the deletion of, or polymorphisms in, the CDK4I gene. The invention is therefore directed to the gene (CDK4I), the inhibitor protein, as well as therapeutic and diagnostic methods which utilize both the CDK4I gene and the CDK4I protein.

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Inventors:

カーソン、デニスエー．
ノボリ、ツトム

Application Number:

JP52712895A

Publication Date:

December 02, 1997

Filing Date:

April 12, 1995

Export Citation:

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Assignee:

ザリージェンツオブザユニバーシティオブカリフォルニア

International Classes:

C12N15/09; A61K38/00; A61P35/00; C07H21/04; C07K14/47; C07K14/82; C07K16/18; C07K16/32; C12P21/02; C12P21/08; C12Q1/02; C12Q1/68; G01N33/53; (IPC1-7): C12N15/09; A61K38/00; C07H21/04; C07K14/82; C07K16/32; C12Q1/68; G01N33/53

Attorney, Agent or Firm:

中島淳（外４名）

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