Title:
両親媒性ポリ(N-ビニル-2-ピロリドン)コポリマーの調整法
Document Type and Number:
Japanese Patent JP5085134
Kind Code:
B2
Abstract:
The instant invention provides a two-step polymerization process for preparing amphiphilic poly(N-vinyl-2 pyrrolidone), (PVP)-block-polyester copolymers and other diblock and triblock copolymers consisting of PVP as one block. The block copolymers of the invention can be used as vehicles for drug delivery.
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Inventors:
Luo Rabin
Resart david
Gori Sandra
Ranger maxim
One Yuan
Rafreniel Julie
Munich Gene-Frances
Vibe Genevieve
Leblanc Frederick
Route way
Resart david
Gori Sandra
Ranger maxim
One Yuan
Rafreniel Julie
Munich Gene-Frances
Vibe Genevieve
Leblanc Frederick
Route way
Application Number:
JP2006541773A
Publication Date:
November 28, 2012
Filing Date:
December 01, 2004
Export Citation:
Assignee:
Labo Pharma Inc.
International Classes:
C08G63/78; C08F26/10; C08F265/04; C08F293/00; C08F297/00; C08F297/02; C08K5/05; C08L53/00
Domestic Patent References:
| JP8510278A |
Other References:
A. Benahmed, M. Ranger, and J.-C. Leroux,Novel Polymeric Micelles Based on the Amphiphilic Diblock Copolymer Poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide),Pharmaceutical Research,Plenum Publishing Corporation,2001年 3月,Vol.18, No.3,323-328
K.M. Stridsberg, M. Ryner, A.-C. Albertsson,Controlled Ring-Opening Polymerization: Polymers with designed Macromolecular Architecture,Advances in Polymer Science,ドイツ,Springer-Verlag Berlin Heidelberg,2002年,Vol.157,41-65
L. Luo et al,Novel Amphiphilic Diblock Copolymer of Low Molecular Weight Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide): Synthesis, Characterization, and Micellization,Macromolecules,米国,American Chemical Society,2004年,Vol.37,4008-4013
K.M. Stridsberg, M. Ryner, A.-C. Albertsson,Controlled Ring-Opening Polymerization: Polymers with designed Macromolecular Architecture,Advances in Polymer Science,ドイツ,Springer-Verlag Berlin Heidelberg,2002年,Vol.157,41-65
L. Luo et al,Novel Amphiphilic Diblock Copolymer of Low Molecular Weight Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide): Synthesis, Characterization, and Micellization,Macromolecules,米国,American Chemical Society,2004年,Vol.37,4008-4013
Attorney, Agent or Firm:
Masahiro Abe