Title:
4-メチル-チアゾール-5-カルボアルデヒド中間体を調製する方法。
Document Type and Number:
Japanese Patent JP2005526112
Kind Code:
A
Abstract:
The present invention provides a process for the preparation of 4-methyl-5-formyl-thiazole of the formula (I)which comprises reducing the thiazole ester of the formula (III) to thiazole alcohol of the formula (IV), using sodium borohydride in the presence of AlCl3 in a solvent and oxidising using an oxidizing agent the thiazole alcohol of the formula (IV) to obtain 4-methyl-5-formyl-thiazole of the formula (I).
Inventors:
Deshpande, Pandurang, Balwand
Rusla, Parven, Kumar
Vias, Lajesh
Comma, Ramakrishna
Rusla, Parven, Kumar
Vias, Lajesh
Comma, Ramakrishna
Application Number:
JP2003587790A
Publication Date:
September 02, 2005
Filing Date:
December 10, 2002
Export Citation:
Assignee:
ORCHID CHEMICALS & PHARMACEUTICALS LIMITED
International Classes:
C07B61/00; C07D277/24; C07D277/56; C07D501/24; (IPC1-7): C07D277/24; C07D501/24
Attorney, Agent or Firm:
Ken Takahashi