Title:
A method for prevention of colon excision
Document Type and Number:
Japanese Patent JP6193248
Kind Code:
B2
Abstract:
The present invention relates to methods of preventing or reducing the need of colectomy. In particular, the present invention relates to an oligonucleotide, for use in the treatment of an inflammatory bowel disease, such as ulcerative colitis (UC) or Crohn's disease, in a subject that is refractory or responds insufficiently or is intolerant to anti-inflammatory therapy, wherein said oligonucleotide is repetitively administered as a single exposure.
Inventors:
Admure, Carlotte
Tsargari, Arezzo
Von stein, oliver
Von Stein, Petra
Tsargari, Arezzo
Von stein, oliver
Von Stein, Petra
Application Number:
JP2014542858A
Publication Date:
September 06, 2017
Filing Date:
November 23, 2012
Export Citation:
Assignee:
InDex Pharmaceuticals AB
International Classes:
A61K31/7125; A61K31/711; A61P1/04; A61P37/02
Domestic Patent References:
| JP2008544983A |
Foreign References:
| WO2006132204A1 | ||||
| WO2010053435A1 |
Other References:
THOMSON REUTERS INTEGRITY,DIMS0150 as rectal therapy in steroid refractory ulcerative colitis? 以下備考,INTERNET CITATION [ONLINE],2009年11月21日,Results from a placebo controlled randomized trial,URL,http://integrity.thomson-pharma.com/integrity/xmlxsl/pk_ref_list.xml_show_ficha_ref?p_ref_id=1422621
Antisense NF-κBp65 oligonucleotide for the treatment of active ulcerative colitis,2002年,pp.1-4
Gut,2005年,Vol.54,pp.503-509
Antisense NF-κBp65 oligonucleotide for the treatment of active ulcerative colitis,2002年,pp.1-4
Gut,2005年,Vol.54,pp.503-509
Attorney, Agent or Firm:
Patent business corporation Kita Aoyama International