Title:
脂溶性ポリフェノール成分が増加した生薬組成物の製造方法、前記方法で製造された生薬組成物、及びその用途
Document Type and Number:
Japanese Patent JP6581721
Kind Code:
B2
Abstract:
The present invention relates to a method for preparing an herbal composition with increased fat-soluble polyphenols, an herbal composition prepared by the method, and a use of the composition. The herbal composition with increased fat-soluble polyphenols of the present invention is characterized by the significantly increased content of fat-soluble polyphenols including decursin, compared with the herbal composition of comparative example, and also demonstrates a significant anti-oxidative activity, immune cell activating effect, and cancer cell growth inhibitory effect, significantly reduces renal toxicity and liver toxicity induced by the anticancer agent cisplatin back so as to be almost normal condition, and significantly inhibits the intestinal crypt loss caused by irradiation, compared with the herbal composition of comparative example. Therefore, the herbal composition with increased fat-soluble polyphenols of the present invention can be effectively used as a composition for cancer treatment, an anti-cancer adjuvant, a composition for enhancing immune function, a composition for protecting a living body, and a composition for preventing side effects of cancer treatment.
Inventors:
Cho Sung-key
Park Helan
John Yui
Lee Hoyoung
Cho Hyang Hee
Park Helan
John Yui
Lee Hoyoung
Cho Hyang Hee
Application Number:
JP2018516790A
Publication Date:
September 25, 2019
Filing Date:
October 10, 2016
Export Citation:
Assignee:
Korea Atomic Energy Research Institute
International Classes:
A61K36/232; A23L33/105; A61K31/37; A61K31/7048; A61K36/234; A61K36/65; A61P35/00; A61P37/04; A61P39/06
Domestic Patent References:
| JP2004307458A | ||||
| JP2010222293A | ||||
| JP2009001513A | ||||
| JP2014136679A | ||||
| JP2012193157A |
Other References:
Chem Pharm Bull,2015年 5月,Vol.63,p.504-511
Kor J Pharmacogn,2009年,Vol.40, No.4,p.293-302
Kor J Pharmacogn,2009年,Vol.40, No.4,p.293-302
Attorney, Agent or Firm:
Patent Business Corporation Saegusa International Patent Office