Title:
標的タンパク質を含むエキソソームの生成方法及びこの生成方法によって生成されたエキソソームを使用することによるサイトゾルへの標的タンパク質の移行方法
Document Type and Number:
Japanese Patent JP6878305
Kind Code:
B2
Abstract:
The present invention relates to a method for the mass-production of exosome comprising a target protein, a vector for preparing the exosome, exosome including a target protein prepared by the method, and a method for loading the target protein to cytosol by using the exosome prepared thereby. According to the method for preparing an exosome comprising a target protein provided by the present invention, the exosome loaded with a target protein can be produced with a high yield, so that it can be used broadly in the treatment of disease using the exosome.
Inventors:
Choi, to Churu
Im, nan bin
Heo, Wand
Ryu, Sun-Wook
Choi, Fujun
Choi, Kyun Sun
Im, nan bin
Heo, Wand
Ryu, Sun-Wook
Choi, Fujun
Choi, Kyun Sun
Application Number:
JP2017558377A
Publication Date:
May 26, 2021
Filing Date:
May 04, 2016
Export Citation:
Assignee:
Iliad Biologics Incorporated
International Classes:
C12N15/62; A61K38/02; A61K47/42; C07K19/00; C12N1/00; C12N15/63; C12P21/02
Foreign References:
| US20130078658 |
Other References:
Nature Biotechnol., 2009年,Vol.27, No.10,p.941-945
Attorney, Agent or Firm:
Hiraki International Patent Office