Title:
EVH1ドメインまたはEVH1ドメインを有するタンパク質とEVH1結合ドメインまたはEVH1結合ドメインを有するタンパク質との相互作用を調節する化合物をスクリーニングする方法およびその相互作用を検出する方法
Document Type and Number:
Japanese Patent JP4437003
Kind Code:
B2
Abstract:
The invention relates to processes for identifying chemical compounds which are capable of modulating the interaction between VASP and zyxin. VASP or a VASP derivative and zyxin or a zyxin derivative which interact with one another are brought into contact with a chemical compound to be examined. The effect on the interaction can be determined using antibodies against VASP or a VASP derivative and/or zyxin or a zyxin derivative, or with the aid of fluorescent labels on VASP or a VASP derivative and zyxin or a zyxin derivative.
Inventors:
Birgit Jordan
Peter Druckes
Thomas Yarshaw
Ulrich Walter
Peter Druckes
Thomas Yarshaw
Ulrich Walter
Application Number:
JP2002544665A
Publication Date:
March 24, 2010
Filing Date:
November 22, 2001
Export Citation:
Assignee:
Sanofi-Aventis Deutschland Gesellschaft Mitt Beschlenktel Haftung
Vasofarm Biotech Game Beer
Vasofarm Biotech Game Beer
International Classes:
G01N33/566; A61K38/00; A61K45/00; A61P9/00; A61P29/00; A61P35/00; A61P43/00; C07K14/47; C07K16/18; C12N5/10; C12P21/08; G01N33/15; G01N33/50; G01N33/53; G01N33/68
Foreign References:
| WO1998001755A1 | ||||
| WO1999011814A1 | ||||
| WO2000048621A1 |
Attorney, Agent or Firm:
Chika Takagi