Title:
A method for seeking Enshingu of the biomolecule by detecting the relative position of the hybridized probe
Document Type and Number:
Japanese Patent JP5998148
Kind Code:
B2
Abstract:
A sequencing method is presented in which a biomolecule is hybridized with a specially chosen pool of different probes of known sequence which can be electrically distinguished. The different probe types are tagged such that they can be distinguished from each other in a Hybridization Assisted Nanopore Sequencing (HANS) detection system, and their relative positions on the biomolecule can be determined as the biomolecule passes through a pore or channel. The methods eliminate, resolve, or greatly reduce ambiguities encountered in previous sequencing methods.
Inventors:
Goldstein, Peter H.
Application Number:
JP2013538841A
Publication Date:
September 28, 2016
Filing Date:
November 09, 2011
Export Citation:
Assignee:
Nabsis 2.0 LLC
International Classes:
C12Q1/68; C12M1/00; C12N15/09; G01N33/53; G06F19/20
Domestic Patent References:
| JP2002519011A | ||||
| JP2005511018A |
Foreign References:
| WO2009046094A1 | ||||
| WO2010138136A1 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto