Title:
A method for supervising a reaction
Document Type and Number:
Japanese Patent JP6100736
Kind Code:
B2
Abstract:
The invention describes a method for the synthesis of compounds comprising the steps of: (a) compartmentalising two or more sets of primary compounds into microcapsules; such that a proportion of the microcapsules contains two or more compounds; and (b) forming secondary compounds in the microcapsules by chemical reactions between primary compounds from different sets. The invention further allows for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, and which is co-compartmentalised into the microcapsules.
Inventors:
Griffiths, Andrew David
Abel, chris
Holfelder, florian
Mastrobatista, Enrico
Abel, chris
Holfelder, florian
Mastrobatista, Enrico
Application Number:
JP2014144285A
Publication Date:
March 22, 2017
Filing Date:
July 14, 2014
Export Citation:
Assignee:
Medical Research Council
International Classes:
C12Q1/00; B01J19/00; C07K1/04; C09K23/20; C12N15/10; C12Q1/66; C12Q1/68; C40B20/08; C40B30/00; C40B30/10; C40B40/04; G01N33/543; C40B40/06; C40B40/10; C40B50/08
Domestic Patent References:
| JP2002534085A | ||||
| JP2001149081A |
Foreign References:
| US20020058332 | ||||
| WO2001075435A1 |
Other References:
Eur. J. Biochem.,1988年,Vol.173,pp.401-409
Biochemistry,1993年,Vol.32,pp.4029-4034
Eur. J. Biochem.,1991年,Vol.199,pp.95-103
Promega,ハイスループットアプリケーションにおけるアポトーシスの迅速検出,Prometech Journal [online],2001年,No.06 (PJ006), 検索日2015.08.07
Angew. Chem. Int. Ed.,2003年,Vol.42, No.7,pp.767-772
Biochemistry,1993年,Vol.32,pp.4029-4034
Eur. J. Biochem.,1991年,Vol.199,pp.95-103
Promega,ハイスループットアプリケーションにおけるアポトーシスの迅速検出,Prometech Journal [online],2001年,No.06 (PJ006),
Angew. Chem. Int. Ed.,2003年,Vol.42, No.7,pp.767-772
Attorney, Agent or Firm:
Shoichi Okuyama
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura
Arihara Koichi
Matsushima Tetsuo
Hidefumi Kawamura