Title:
A modulator of an ATP joint cassette transporter
Document Type and Number:
Japanese Patent JP6158985
Kind Code:
B2
Abstract:
The present invention relates to an intermediate compound of modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"), compositions thereof which may be used in and methods of treating ABC transporter mediated diseases; namely to 1-(2,2-Difluoro-benzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid.
Inventors:
Sara S. Hadida Rua
Peter Dee. Jay. Groten Huis
Mark Tee. Mirror
Matthew Hamilton
Peter Dee. Jay. Groten Huis
Mark Tee. Mirror
Matthew Hamilton
Application Number:
JP2016097613A
Publication Date:
July 05, 2017
Filing Date:
May 16, 2016
Export Citation:
Assignee:
VERTEX PHARMACEUTICALS INCORPORATED
International Classes:
C07D317/46; C07D231/40; C07D233/88; C07D263/48; C07D271/113; C07D277/46; C07D277/54; C07D277/82; C07D285/135; C07D405/12; C07D407/12; C07D409/12; C07D409/14; C07D413/12; C07D417/04; C07D417/06; C07D417/12; C07D417/14; C07D493/10; C07D271/10; C07D285/12
Domestic Patent References:
| JP2002155065A |
Foreign References:
| WO2003088908A1 | ||||
| WO2003074515A1 | ||||
| WO1999024035A1 | ||||
| WO2001085726A1 | ||||
| WO2003053915A1 | ||||
| WO2001036415A1 | ||||
| WO2001046165A1 | ||||
| WO2005051919A1 |
Attorney, Agent or Firm:
Takeshi Oshio
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