Title:
ブプレノルフィンおよびその代謝産物に特異的なモノクローナル抗体
Document Type and Number:
Japanese Patent JP2007537972
Kind Code:
A
Abstract:
The present invention relates to monoclonal antibodies that specifically bind buprenorphine and/or at least one metabolic product thereof. The present invention further relates to buprenorphine metabolite conjugates for the production of monoclonal antibodies that specifically bind buprenorphine and/or at least one metabolic product thereof and hybridoma cells that produce the monoclonal antibodies. The invention also relates to immunoassay methods for determining buprenorphine and/or one or more buprenorphine metabolites in a sample using the novel antibodies and conjugates of the present invention.
Inventors:
Root, Richard, Tee.
Goshall, mitari
Goshall, mitari
Application Number:
JP2006508245A
Publication Date:
December 27, 2007
Filing Date:
June 02, 2004
Export Citation:
Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
C07K16/18; C07D498/12; C07K16/44; C12N5/10; G01N33/53; G01N33/94; C07K14/76; C12P21/08
Attorney, Agent or Firm:
Yoshinori Hosoda