Title:
The monoclonal antibody to pro gastrin, and its use
Document Type and Number:
Japanese Patent JP5985987
Kind Code:
B2
Abstract:
The present disclosure is directed to progastrin monoclonal antibodies, fragments thereof, compositions comprising progastrin monoclonal antibodies, and methods of making and using progastrin monoclonal antibodies and compositions thereof. The present disclosure is directed to methods of treating colorectal cancer with progastrin monoclonal antibodies and compositions comprising progastrin monoclonal antibodies or fragments thereof. The present disclosure is further directed to methods comprising detection of progastrin, including methods of diagnosing colorectal cancer and methods of monitoring efficacy of anti-cancer therapy in subjects suffering from colorectal cancer.
Inventors:
Panekan, Julie
Budier roll
Joubert, Dominique
Frederik, Holland
Budier roll
Joubert, Dominique
Frederik, Holland
Application Number:
JP2012533531A
Publication Date:
September 06, 2016
Filing Date:
October 15, 2010
Export Citation:
Assignee:
Réra Bora Toir Servier
Institut National De La Sante & De La Recherche Medical
Institut National De La Sante & De La Recherche Medical
International Classes:
C12N15/09; A61K39/395; A61P1/00; A61P35/00; C07K16/26; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N5/12; C12P21/08; G01N33/574
Domestic Patent References:
| JP2008513536A |
Foreign References:
| WO2007135542A2 |
Attorney, Agent or Firm:
Patent business corporation Tsukuni