Title:
ナノスケール白金化合物およびその使用方法
Document Type and Number:
Japanese Patent JP2012516898
Kind Code:
A
Abstract:
The invention is directed to biocompatible conjugated polymer nanoparticles including a copolymer backbone, a plurality of sidechains covalently linked to said backbone, and a plurality of platinum compounds dissociably linked to said backbone. The invention is also directed to dicarbonyl-lipid compounds wherein a platinum compound is dissociably linked to the dicarbonyl compound. The invention is also directed to methods of treating cancer or metastasis. The methods includes selecting a subject in need of treatment for cancer or metastasis and administering to the subject an effective amount of any of the nanoparticles, compounds, or compositions of the invention.
Inventors:
Sengtupa Siradicha
Parascar Abimanyu
Soni shibani
Bus splitter
Sengtupa Pouromi
Parascar Abimanyu
Soni shibani
Bus splitter
Sengtupa Pouromi
Application Number:
JP2011549262A
Publication Date:
July 26, 2012
Filing Date:
February 04, 2010
Export Citation:
Assignee:
The Brigham And Women's Hospital Incorporated
International Classes:
A61K31/282; A61K9/107; A61K9/127; A61K9/14; A61K33/243; A61K47/28; A61K47/32; A61K47/34; A61K47/48; A61P35/00; C08F22/00
Domestic Patent References:
| JP2008509205A | 2008-03-27 | |||
| JP2008509205A | 2008-03-27 |
Foreign References:
| US20080145416A1 | 2008-06-19 |
Other References:
JPN6014013509; Ｎａｎｏｔｅｃｈｎｏｌｏｇｙ， ２０１１， ｖｏｌ．２２， ｎｏ．２６：２６５１０１
JPN6014013512; Ｉｎｔ Ｊ Ｐｈａｒｍ， ｖｏｌ．３０９， ｐ．１８９-１９８ （２００６）
JPN6014013498; Ａｎｇｅｗ Ｃｈｅｍ Ｉｎｔ Ｅｄ． ２００６， ｖｏｌ．４５， ｐ．１１９８-１２１５
JPN6014013503; Ｅｕｒ Ｊ Ｃａｎｃｅｒ ｖｏｌ．４０， ｐ．２９１-２９７ （２００４）
JPN6014013506; Ｊ Ａｐｐｌ Ｐｏｌｙｍ Ｓｃｉ， ｖｏｌ．８７， ｐ．１２５５-１２６６ （２００３）
JPN6014013515; ＰＮＡＳ， ｖｏｌ．１０５， ｐ．１７３５６-１７３６１ （２００８）
JPN6014013509; Ｎａｎｏｔｅｃｈｎｏｌｏｇｙ， ２０１１， ｖｏｌ．２２， ｎｏ．２６：２６５１０１
JPN6014013512; Ｉｎｔ Ｊ Ｐｈａｒｍ， ｖｏｌ．３０９， ｐ．１８９-１９８ （２００６）
JPN6014013512; Ｉｎｔ Ｊ Ｐｈａｒｍ， ｖｏｌ．３０９， ｐ．１８９-１９８ （２００６）
JPN6014013498; Ａｎｇｅｗ Ｃｈｅｍ Ｉｎｔ Ｅｄ． ２００６， ｖｏｌ．４５， ｐ．１１９８-１２１５
JPN6014013503; Ｅｕｒ Ｊ Ｃａｎｃｅｒ ｖｏｌ．４０， ｐ．２９１-２９７ （２００４）
JPN6014013506; Ｊ Ａｐｐｌ Ｐｏｌｙｍ Ｓｃｉ， ｖｏｌ．８７， ｐ．１２５５-１２６６ （２００３）
JPN6014013515; ＰＮＡＳ， ｖｏｌ．１０５， ｐ．１７３５６-１７３６１ （２００８）
JPN6014013509; Ｎａｎｏｔｅｃｈｎｏｌｏｇｙ， ２０１１， ｖｏｌ．２２， ｎｏ．２６：２６５１０１
JPN6014013512; Ｉｎｔ Ｊ Ｐｈａｒｍ， ｖｏｌ．３０９， ｐ．１８９-１９８ （２００６）
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Shinichi Watanabe
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto