Title:
人体の好中球エラステーゼと人体カテプシンGの抑制因子
Document Type and Number:
Japanese Patent JP3819931
Kind Code:
B2
Abstract:
The present invention relates to non-naturally occurring proteins which inhibit human neutrophile elastase, which proteins comprise at least the core sequence of a Kunitz domain. Other aspects of the invention relate to pharmaceutical compositions comprising these proteins, and the use of these proteins or compositions for use in medicine, in particular for the preparation of medicaments for the treatment of disorders or diseases associated with excessive human neutrophile elastase activity.
Inventors:
Ray, Arthur, Charles
Radner, Robert, Charles
Gutterman, Sonia, Kosou
Roberts, Bruce, Lindsay
Mark Land, William
Kent, Rachel, Bali Vault
Radner, Robert, Charles
Gutterman, Sonia, Kosou
Roberts, Bruce, Lindsay
Mark Land, William
Kent, Rachel, Bali Vault
Application Number:
JP50820492A
Publication Date:
September 13, 2006
Filing Date:
February 28, 1992
Export Citation:
Assignee:
DYAX CORP.
International Classes:
A61K38/55; C07K14/81; A61K8/64; A61K38/04; A61P11/00; A61P29/00; A61Q11/00; C07K1/04; C07K5/06; C07K5/062; C07K5/065; C07K7/00; C07K14/435; C12N7/00; C12N9/99; C12N15/09; C12N15/10; C40B40/02; A61K38/00
Other References:
Eur.J.Biochem.,153[3](1985)p.647-654
Attorney, Agent or Firm:
Masao Okabe
Nobuaki Kato
Shinichi Usui
Ikuo Fujino
Takao Ochi
Teruhisa Motomiya
Norimichi Takanashi
Nobuaki Kato
Shinichi Usui
Ikuo Fujino
Takao Ochi
Teruhisa Motomiya
Norimichi Takanashi