Title:
抗糖尿病剤として有用な新規な環状ベンゾイミダゾール誘導体
Document Type and Number:
Japanese Patent JP5575137
Kind Code:
B2
Abstract:
Novel compounds of the structural formula (I) are activators of AMP-protein kinase and are useful in the treatment, prevention and suppression of diseases mediated by the AMPK-activated protein kinase. The compounds of the present invention are useful in the treatment of Type 2 diabetes, hyperglycemia, Metabolic Syndrome, obesity, hypercholesterolemia, and hypertension.
Inventors:
A book sir, a bullet, See.
Dan, a can
Gibson, Tony, S.
Chang, Hongjiang
Chun, デ Michael
Bao, Jean Min
Chang, Jin Ron
カシック, Andy
ケケック, an armet
A run, a pin
Lieu, フアガン
Makara, George, M.
Romero, F. Anthony
セブハット, イヤッス
Wilson, David
Vodka, Darius
Dan, a can
Gibson, Tony, S.
Chang, Hongjiang
Chun, デ Michael
Bao, Jean Min
Chang, Jin Ron
カシック, Andy
ケケック, an armet
A run, a pin
Lieu, フアガン
Makara, George, M.
Romero, F. Anthony
セブハット, イヤッス
Wilson, David
Vodka, Darius
Application Number:
JP2011533227A
Publication Date:
August 20, 2014
Filing Date:
October 12, 2009
Export Citation:
Assignee:
Merck sharp and dome corporation Merck Sharp & Dohme Corp.
Meta-バシス Therapeutics, Incorporated METABASIS THERAPEUTICS, INC.
Meta-バシス Therapeutics, Incorporated METABASIS THERAPEUTICS, INC.
International Classes:
A61K31/366; C07F9/6506; A61K31/397; A61K31/44; A61K31/4985; A61K31/675; A61P3/04; A61P3/06; A61P3/10; A61P9/12; A61P35/00; A61P43/00; C07F9/6558; C07F9/6571; C07F9/6574
Attorney, Agent or Firm:
Iwase Yoshiwa
Makoto Ono
Yoshinori Kanayama
Michiaki Tsubokura
Kazuteru Shigemori
Yasufumi Shiroyama
Kenji Ando
Kenji Ando
Makoto Ono
Yoshinori Kanayama
Michiaki Tsubokura
Kazuteru Shigemori
Yasufumi Shiroyama
Kenji Ando
Kenji Ando