Title:
ステロイド/非ステロイド抗炎症活性分子、抗新生物活性分子および抗ウイルス活性分子用担体としての新規な化合物、組成物
Document Type and Number:
Japanese Patent JP4530851
Kind Code:
B2
Abstract:
The present invention relates (a) to new compounds represented by Formula I: wherein M represents a macrolide subunit (macrolide moiety) derived from macrolide possessing the property of accumulation in inflammatory cells, V represents an anti-inflammatory steroid or nonsteroid subunit, or an antineoplastic or antiviral subunit and L represents a linking group covalently linking M and V; (b) to their pharmacologically acceptable salts, prodrugs and solvates, (c) to processes and intermediates for their preparation, and (d) to their use in the treatment of inflammatory/neoplastic/viral diseases and conditions in humans and animals.
Inventors:
Muraden Mercep
Milan Mesic
Linda Tomaskovich
Stribol Malkovich
Milan Mesic
Linda Tomaskovich
Stribol Malkovich
Application Number:
JP2004519131A
Publication Date:
August 25, 2010
Filing Date:
July 08, 2003
Export Citation:
Assignee:
GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O.
International Classes:
A61K47/48; C07K5/103; A61K31/58; A61K31/585; A61P1/00; A61P1/04; A61P9/10; A61P11/00; A61P11/06; A61P11/08; A61P17/00; A61P17/04; A61P17/06; A61P19/02; A61P19/06; A61P21/00; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P31/18; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07J17/00; C07J43/00; C07K5/083; C07K5/10
Domestic Patent References:
| JP2004518670A |
Attorney, Agent or Firm:
Mitsuo Tanaka
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita
Hiroshi Yamazaki
Tadayuki Motoyama
Kenji Tomita