【発明の名称】新規の局所麻酔組成物およびその使用

Title:

【発明の名称】新規の局所麻酔組成物およびその使用

Document Type and Number:

Japanese Patent JP2002510669

Kind Code:

A

Abstract:

Novel compounds, pharmaceutical compositions and methods are disclosed for producing local anesthesia of long-duration. The compounds of this invention are multibinding compounds that comprise from 2 to 10 ligands covalently attached to a linker or linkers, each ligand being capable of binding to a ligand binding site in a voltage-gated Na+ channel to modulate the biological processes/functions thereof.

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Inventors:

Axt, Sabine M.
Church, Timothy Jay.
Losewitz, Whitold
Jacobsen, John Earl.
Jenkins, Thomas E.
The, Yufa
Judith, Kevin Jay.

Application Number:

JP2000542287A

Publication Date:

April 09, 2002

Filing Date:

April 02, 1999

Export Citation:

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Assignee:

Advanced Medicine Incorporated

International Classes:

A61K31/16; A61K31/33; A61K31/395; A61K31/445; A61P23/02; A61P25/04; C07C233/04; C07C237/04; C07C237/34; C07D211/60; C07D211/62; C07D255/02; C07D241/12; C07D273/00; C07D273/08; (IPC1-7): C07C233/04; A61K31/16; A61K31/33; A61K31/395; A61K31/445; A61P23/02; A61P25/04; C07D211/62; C07D241/12; C07D255/02; C07D273/08

Attorney, Agent or Firm:

Shusaku Yamamoto

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