A new method - Novartis Age

Title:

A new method

Document Type and Number:

Japanese Patent JP6280119

Kind Code:

B2

Abstract:

The invention relates to a new enantioselective process for producing useful intermediates for the manufacture of NEP inhibitors or prodrugs thereof, in particular NEP inhibitors comprising a γ-amino-δ-biphenyl-α-methylalkanoic acid, or acid ester, backbone.

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Inventors:

Chu, Golyang
Ye Wenfa
Zen
Chin, Rinphen
Way, Junfi
Yang, Lee Jun
Lee, junguang
Luo, Lee Jun

Application Number:

JP2015528863A

Publication Date:

February 14, 2018

Filing Date:

September 02, 2013

Export Citation:

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Assignee:

Novartis Age

International Classes:

C07C29/40; C07C213/02; C07C33/46; C07C41/30; C07C43/178; C07C215/28; C07C269/04; C07C269/06; C07C271/16; C07C271/18; C07C271/22; C07D207/404; C07D209/48

Domestic Patent References:

JP2009506066A

Foreign References:

WO1999002153A1
CN101362708A
US5587494

Other References:

Chang, Shaohua; Zhang, Zhang; Zhuang, Xiaoxi; Luo, Jinfeng; Cao, Xianwen; Li, Honglin; Tu, Zhengchao; Lu, Xiaoyun; Ren, Xiaomei; Ding, Ke,New thiazole carboxamides as potent inhibitors of Akt kinases,Bioorganic & Medicinal Chemistry Letters,2012年,22(2),1208-1212

Attorney, Agent or Firm:

Hiroshi Kobayashi
Norio Omori
Saori Oga
Yasuhito Suzuki

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