Title:
新規な置換スルファメート抗痙攣性誘導体
Document Type and Number:
Japanese Patent JP2005526852
Kind Code:
A
Abstract:
The present invention is directed to novel compounds of the formula (I) wherein X, R1, R2, R3, R4, R5 and R6 are as described in the specification, processes for the preparation of and pharmaceutical compositions comprising said derivatives. The compounds of the present invention are useful for the treatment of epilepsy. The invention is further directed to a process for the preparation of compounds of formula (XX), wherein X, R3, R4, R5 and R6 are as described in the specification.
Inventors:
Abdel-Majid, Ahmed
Marianov, Cynthia
Meerman, Stephen
Sausage, kirk
Billani, Frank
Kodiek, Sieri Rupee
Rights, allen bee
Marianov, Bruce Elliotto
Marianov, Cynthia
Meerman, Stephen
Sausage, kirk
Billani, Frank
Kodiek, Sieri Rupee
Rights, allen bee
Marianov, Bruce Elliotto
Application Number:
JP2004505387A
Publication Date:
September 08, 2005
Filing Date:
May 09, 2003
Export Citation:
Assignee:
Ortho-McNeill Pharmacy Incorporated
International Classes:
A61K31/7004; A61P25/08; C07H5/06; C07H9/02; C07H9/04; (IPC1-7): C07H9/02; A61K31/7004; A61P25/08
Domestic Patent References:
| JPH07291988A | 1995-11-07 | |||
| JPH09507070A | 1997-07-15 | |||
| JP2000502888A | 2000-03-14 | |||
| JPS60109558A | 1985-06-15 |
Other References:
JPN6009064651, ＭＡＲＹＡＮＯＦＦ， Ｂ．Ｅ．， ｅｔ ａｌ．, Ｊ． Ｍｅｄ． Ｃｈｅｍ．, ４１（８）, ｐｐ．１３１５−１３４３ （１９９８）
JPN6009064652, ＢＡＲＲＩＯＳ， Ｉ．Ａ．， ｅｔ ａｌ．, ＴＨＥＯＣＨＥＭ, ５８０, ｐｐ．２４３−２５０ （２００２）
JPN6009064653, ＭＡＲＹＡＮＯＦＦ， Ｂ．Ｅ．， ｅｔ ａｌ．, Ｂｉｏｏｒｇ． Ｍｅｄ． Ｃｈｅｍ． Ｌｅｔｔ．, ３（１２）, ｐｐ．２６５３−２６５６ （１９９３）
JPN6009064652, ＢＡＲＲＩＯＳ， Ｉ．Ａ．， ｅｔ ａｌ．, ＴＨＥＯＣＨＥＭ, ５８０, ｐｐ．２４３−２５０ （２００２）
JPN6009064653, ＭＡＲＹＡＮＯＦＦ， Ｂ．Ｅ．， ｅｔ ａｌ．, Ｂｉｏｏｒｇ． Ｍｅｄ． Ｃｈｅｍ． Ｌｅｔｔ．, ３（１２）, ｐｐ．２６５３−２６５６ （１９９３）
Attorney, Agent or Firm:
Heikichi Odashima