Title:
NOVEL TARGET FOR DIAGNOSIS AND TREATMENT OF DIABETES AND CARDIOVASCULAR DISEASES
Document Type and Number:
Japanese Patent JP2017171682
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide diagnostics and therapeutics for diabetes, atherosclerosis, and other cardiovascular diseases.SOLUTION: The invention provides diagnostic, prognostic and treatment methods, compositions and kits for enhancing insulin secretion and β cell numbers and functions, and controlling glycemia associated with diabetes, obesity, atherosclerosis, stroke, myocardial infarction, and other cardiovascular diseases, by modulating FKN/CX3CR1 expression levels or activities, and its downstream signaling pathways in a subject in need or at risk.SELECTED DRAWING: Figure 13
Inventors:
JERROLD M OLEFSKY
LEE YUN SOK
LEE YUN SOK
Application Number:
JP2017122785A
Publication Date:
September 28, 2017
Filing Date:
June 23, 2017
Export Citation:
Assignee:
UNIV CALIFORNIA
International Classes:
A61K38/19; A61K45/00; A61P3/04; A61P3/10; A61P5/50; A61P9/00; A61P9/10; A61P43/00; C12Q1/68; G01N33/53
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Toshifumi Onuki
Akihiko Eguchi
Kazuhiko Naito
Previous Patent: The process for generation of the EPO Xide to acrylate
Next Patent: RAGE gene expression depressant
Next Patent: RAGE gene expression depressant