Title:
アゴニストまたはアンタゴニストホルモン特性を有する17β-ニトロ-11β-アリルステロイドとその誘導体
Document Type and Number:
Japanese Patent JP4545930
Kind Code:
B2
Abstract:
The invention is directed to 17 beta -nitro-11 beta -arylsteroids of formula I: wherein R1, R6, R7, R12 and X are as defined by the specification. The compounds exhibit potent antiprogestational activity and are useful in the treatment of fibroids, endometriosis, cervical ripening prior to delivery, hormone replacement therapy and in the control of fertility.
More Like This:
Inventors:
Edgar Sea Cook
John A Kepler
Lupa S Shetty
Gerry S. Bartley
David Yue-Way Lee
John A Kepler
Lupa S Shetty
Gerry S. Bartley
David Yue-Way Lee
Application Number:
JP2000552139A
Publication Date:
September 15, 2010
Filing Date:
May 28, 1999
Export Citation:
Assignee:
Research Triangle Institute
International Classes:
C07J43/00; A61K31/56; A61K31/58; A61K45/06; A61P15/00; A61P35/00; A61P43/00; C07J41/00
Domestic Patent References:
| JP3505582A | ||||
| JP5255380A | ||||
| JP59157099A |
Foreign References:
| WO1997041145A1 | ||||
| US4447424 | ||||
| US4634695 | ||||
| US3187022 | ||||
| DE1643034A |
Attorney, Agent or Firm:
Masatake Shiga
Tadashi Takahashi
Takashi Watanabe
Masakazu Aoyama
Suzuki Mitsuyoshi
Kazuya Nishi
Yasuhiko Murayama
Shinya Mitsuhiro
Tadashi Takahashi
Takashi Watanabe
Masakazu Aoyama
Suzuki Mitsuyoshi
Kazuya Nishi
Yasuhiko Murayama
Shinya Mitsuhiro