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Title:
【発明の名称】Aβタンパク質産生の阻害剤としてのサクシノイルアミノ複素環
Document Type and Number:
Japanese Patent JP2003529594
Kind Code:
A
Abstract:
This invention relates to a novel succinoylamino heterocycles of Formula (I) having drug and bio-affecting properties, their pharmaceutical compositions and methods of use. These novel compounds inhibit the processing of amyloid precursor protein and, more specifically, inhibit the production of A beta -peptide, thereby acting to prevent formation of neurological deposits of amyloid protein. More particularly, the present invention relates to the treatment of neurological disorders related to beta -amyloid production such as Alzheimer's disease and Down's Syndrome.

Inventors:
Laurin Andrew Thompson
Padma jakashi lady
Application Number:
JP2001572489A
Publication Date:
October 07, 2003
Filing Date:
March 30, 2001
Export Citation:
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Assignee:
Bristol-Myers Squibb Pharma Company
International Classes:
C07D295/18; A61K31/401; A61K31/4418; A61K31/4439; A61K31/445; A61K31/4468; A61K31/4525; A61K31/454; A61K31/4545; A61K31/455; A61K31/47; A61K31/495; A61K31/496; A61K31/498; A61K31/506; A61P25/28; A61P43/00; C07D207/09; C07D207/16; C07D211/08; C07D211/22; C07D211/26; C07D211/32; C07D211/38; C07D211/42; C07D211/46; C07D211/52; C07D211/56; C07D211/58; C07D211/60; C07D211/62; C07D211/64; C07D211/66; C07D211/70; C07D213/38; C07D213/74; C07D215/08; C07D235/26; C07D239/42; C07D241/04; C07D241/20; C07D241/42; C07D295/185; C07D317/06; C07D317/58; C07D401/04; C07D401/06; C07D405/04; C07D405/12; (IPC1-7): C07D207/09; A61K31/401; A61K31/4418; A61K31/4439; A61K31/445; A61K31/4468; A61K31/4525; A61K31/454; A61K31/4545; A61K31/455; A61K31/47; A61K31/495; A61K31/496; A61K31/498; A61K31/506; A61P25/28; A61P43/00; C07D207/16; C07D211/08; C07D211/22; C07D211/26; C07D211/32; C07D211/38; C07D211/42; C07D211/46; C07D211/52; C07D211/56; C07D211/58; C07D211/60; C07D211/62; C07D211/64; C07D211/66; C07D211/70; C07D213/74; C07D215/08; C07D235/26; C07D239/42; C07D241/04; C07D241/20; C07D241/42; C07D295/18; C07D317/06; C07D401/04; C07D401/06; C07D405/12
Attorney, Agent or Firm:
Yoshikazu Tani (2 outside)