Title:
非ステロイド型男性ホルモン受容体作用剤、その調製方法、薬学組成物及び用途
Document Type and Number:
Japanese Patent JP2008542210
Kind Code:
A
Abstract:
Nons-teroidal androgen receptor modulating compounds of the general formula (I), their pharmaceutically acceptable salts, preparation process and pharmaceutically compositions containing the said compounds are disclosed. Such compounds of the general formula (I) or their pharmaceutically acceptable salts can be used for preparing non-steroidal medicines to treat and/or prevent condictions or diseases such as prostatic hyperplasia, prostate cancer, hirsutism, severe hormone-dependent alopecia or acne, etc. as a result of androgen receptor antagonistic activities.
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Inventors:
Ming Wei
Den Yu
Zhou Chong
Yang Taisei
Ye Xin
S
High rank
Den Yu
Zhou Chong
Yang Taisei
Ye Xin
S
High rank
Application Number:
JP2008512676A
Publication Date:
November 27, 2008
Filing Date:
May 26, 2006
Export Citation:
Assignee:
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
International Classes:
C07C225/16; A61K31/136; A61K31/137; A61K31/196; A61K31/341; A61K31/4453; A61P13/08; A61P15/08; A61P17/10; A61P35/00; C07C209/60; C07C209/68; C07C211/52; C07C213/00; C07C215/28; C07C221/00; C07C229/60; C07D295/10; C07D307/52
Domestic Patent References:
| JPH04187483A | 1992-07-06 |
Foreign References:
| WO2004112690A2 | 2004-12-29 |
Attorney, Agent or Firm:
Kenji Yoshida
Jun Ishida
Jun Ishida