Title:
【発明の名称】ヌクレオシドおよびヌクレオチド標識のための非スルホン化シアニン色素
Document Type and Number:
Japanese Patent JP2002507203
Kind Code:
A
Abstract:
A chemical compound of the following formula: wherein R1 is selected from the group consisting of alkyl, aralkyl, and substituted alkyl groups; R3 is selected from the group consisting of H, PO3-2, P2O6-3; P3O9-4, and alpha -thio phoshates (PSO2-2; P2SO5-3; P3O8-4); and alpha BH3- phosphates (P(BH3)O2-2, P2(BH3)O5-3, P3(BH3)O8-4); R4 is selected from the group consisting of H, lower alkyl, acyl, (CH2)pCOO(CH2)qCH3 wherein p is an integer from 0 to 4 and q is an integer from 0 to 4, and 5,6; 6,7; or 7,8-butadienyl; R5 is selected from the group consisting of H lower alkyl, acyl, (CH2)pCOO(CH2)qCH3 wherein p is an integer from 0 to 4 and q is an integer from 0 to 4 and 5,6; 6,7; or 7,8- butadienyl; r is 1, 2, or 3 to form a second fused aromatic; X or Y are selected from the group consisting of O, S, C(R6)2, or N(R6), wherein R6 is preferably CH3 or a lower alkyl; and R3-O-Sugar-Base is a nucleoside or nucleotide is disclosed.
Inventors:
Blush, Charles Kay
Reimer, Ned Di
Reimer, Ned Di
Application Number:
JP50473699A
Publication Date:
March 05, 2002
Filing Date:
June 16, 1998
Export Citation:
Assignee:
Amersham Pharmacia Biotech Incorporated
International Classes:
C07H19/04; C07H21/00; C12Q1/68; (IPC1-7): C07H19/04; C07H21/00; C12Q1/68
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)