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Title:
【発明の名称】非細胞性(Acellular)百日咳ワクチン及びその調製方法
Document Type and Number:
Japanese Patent JPH11511735
Kind Code:
A
Abstract:
A fimbrial agglutinogen preparation is prepared from a bordetella strain, particularly a B. pertussis strain, by a multiple step procedure involving extraction of the fimbrial agglutinogens from cell paste and concentrating and purifying the extracted material. The fimbrial agglutinogen preparation may be used to prepare acellular pertussis vaccines with other pertussis antigens, including pertussis toxin or toxoid thereof, the 69 kDa protein and filamentous hemagglutinin and other Bordetella antigens.

Inventors:
Vauds, John Earl.
Faheim, Rafat E. F.
Jackson, Gale E. Dee.
Tan, Larry You.
Herbert, Andrew
Boux, leslie
Barreto, Lewis
Tiffauon, John
Klein, Michael H.
Application Number:
JP53288396A
Publication Date:
October 12, 1999
Filing Date:
May 02, 1996
Export Citation:
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Assignee:
Connaught Laboratories Limited
International Classes:
C12N9/10; A61K31/00; A61K38/00; A61K39/05; A61K39/07; A61K39/08; A61K39/10; A61K39/102; A61K39/116; A61K39/13; A61K39/165; A61K39/20; A61K39/29; A61K39/39; A61P31/00; A61P31/04; A61P43/00; C07K14/235; C12P1/00; C12P21/00; A61K39/00; (IPC1-7): A61K39/10; A61K31/00; A61K39/116
Attorney, Agent or Firm:
Wakabayashi Tadashi