Title:
グルタミニルシクラーゼに関連した新規遺伝子
Document Type and Number:
Japanese Patent JP2010504088
Kind Code:
A
Abstract:
The present invention relates to novel glutaminyl-peptide cyclotransferase-like proteins (QPCTLs), which are isoenzymes of glutaminyl cyclase (QC, EC 2.3.2.5), and to isolated nucleic acids coding for these isoenzymes, all of which are useful for the discovery of new therapeutic agents, for measuring cyclase activity, and for determining the inhibitory activity of compounds against these glutaminyl cyclase isoenzymes.
Inventors:
Stephan still ring
Holger Quinis
Jeens-Urlikuf Raffueld
Hans-Urlikuf Demutov
Holger Quinis
Jeens-Urlikuf Raffueld
Hans-Urlikuf Demutov
Application Number:
JP2009528732A
Publication Date:
February 12, 2010
Filing Date:
September 21, 2007
Export Citation:
Assignee:
Probiodor AG
International Classes:
C12N15/09; A61K31/713; A61K38/00; A61P1/04; A61P3/00; A61P9/10; A61P15/08; A61P17/00; A61P17/04; A61P25/00; A61P25/14; A61P25/18; A61P25/20; A61P25/28; A61P29/00; A61P31/04; A61P35/00; A61P35/04; A61P37/06; C07K16/18; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12N9/10; C12Q1/48; G01N33/15; G01N33/50; C12P21/02
Foreign References:
| WO2005108415A2 | 2005-11-17 | |||
| WO2004098625A2 | 2004-11-18 |
Other References:
JPN6012055658; Ｋａｗａｂａｔａ，Ａ．ｅｔ ａｌ．: '"Ａｃｃｅｓｓｉｏｎ：ＡＫ００００９１［ｇｉ：７０１９９５２］，Ｄｅｆｉｎｉｔｉｏｎ：Ｈｏｍｏ ｓａｐｉｅｎｓ ｃＤＮＡ ＦＬＪ２００８４ ｆｉｓ， ｃｌｏｎｅ ＣＯＬ０３５２６．"' ＮＣＢＩ Ｅｎｔｒｅｚ Ｎｕｃｌｅｏｔｉｄｅ［ｏｎｌｉｎｅ］；１２-ＳＥＰ-２００６ ｕｐｌｏａｄｅｄ，ＮＣＢＩ，［ｒｅｔｒｉｅｖｅｄ ｏｎ １９ Ｏｃｔｏｂｅｒ ２０１２］
Attorney, Agent or Firm:
Toru Ishikawa