Title:
キナーゼ活性のモジュレーターとしての新規複素環式誘導体
Document Type and Number:
Japanese Patent JP6386467
Kind Code:
B2
Abstract:
in which R1, R2, W, X1, X2, X3, X4 and n have the meanings indicated in formula I, and their manufacture and use for the treatment of hyperproliferative diseases, such as cancer.
Inventors:
Luo'si Run
Bayyard Earl Hack
Shea Oreen Chen
Yuifan Xiao
Bayyard Earl Hack
Shea Oreen Chen
Yuifan Xiao
Application Number:
JP2015542810A
Publication Date:
September 05, 2018
Filing Date:
November 15, 2013
Export Citation:
Assignee:
Merck Patent Gesellschaft mit beschraenkter Haftung
International Classes:
C07D239/70; A61K31/496; A61K31/517; A61K31/519; A61K31/5383; A61K45/00; A61P9/10; A61P15/00; A61P17/06; A61P19/02; A61P27/02; A61P27/06; A61P29/00; A61P31/04; A61P35/00; C07D471/04; C07D475/06; C07D487/04; C07D498/04
Domestic Patent References:
| JP2008525526A | ||||
| JP2012508274A | ||||
| JP2010514675A | ||||
| JP2009520791A |
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Takahide Sasaki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Takahide Sasaki