Title:
新規のヒドロキシインドール、該ヒドロキシインドールのホスホジエステラーゼ4の阻害剤としての使用および該ヒドロキシインドールの製造法
Document Type and Number:
Japanese Patent JP2006508141
Kind Code:
A
Abstract:
The invention relates to substituted 4- or/and 7-hydroxyindoles, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active compounds for treating diseases which can be influenced by using the compounds according to the invention to inhibit phosphodiesterase 4 activity in immunocompetent cells (e.g. macrophages and lympho-cytes).
Inventors:
Norbert hefgen
Hildegard Cous
Ute Agerland
Chris Rundfeldt
Helga Hartenhauer
Antije Gasparik
Hildegard Cous
Ute Agerland
Chris Rundfeldt
Helga Hartenhauer
Antije Gasparik
Application Number:
JP2004552596A
Publication Date:
March 09, 2006
Filing Date:
November 14, 2003
Export Citation:
Assignee:
elbion AG
International Classes:
C07D209/14; A61K31/404; A61K31/4439; A61K31/444; A61K31/454; A61P9/00; A61P11/00; A61P19/02; A61P29/00; A61P31/18; A61P37/00; A61P43/00; C07D209/22; C07D209/42; C07D401/12; C07D401/14
Attorney, Agent or Firm:
Toshio Yano
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard
Reinhard Einsel
Toshiomi Yamazaki
Takuya Kuno
Einzel Felix-Reinhard
Reinhard Einsel