Title:
アマニチンの新規な合成方法
Document Type and Number:
Japanese Patent JP7165720
Kind Code:
B2
Abstract:
The invention relates to novel methods for synthesizing amanitin derivatives having a hydroxy group attached to the central tryptophan moiety. The invention furthermore relates to novel amanitin derivatives having a hydroxy group attached to position 4′, 5′ or 7′ of the central tryptophan moiety, novel conjugates of such amanitin derivatives, and pharmaceutical compositions comprising such conjugates.
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Inventors:
Lutz Christian
Jimon Werner
Werner Zimon Susanne
Müller Krishtov
Hehiller Torsten
Kurke Michael
Jimon Werner
Werner Zimon Susanne
Müller Krishtov
Hehiller Torsten
Kurke Michael
Application Number:
JP2020506722A
Publication Date:
November 04, 2022
Filing Date:
August 06, 2018
Export Citation:
Assignee:
Heidelberg Pharma Research Gezel Shaft Mitt Beschlenktel Haftung
International Classes:
C07D487/04; A61K38/08; A61K47/51; A61K47/65; A61P35/00; A61P35/02; C07K7/06; C07K7/64
Domestic Patent References:
| JP2014508767A | ||||
| JP2013544231A |
Foreign References:
| US20160220687 | ||||
| WO2014043403A1 |
Attorney, Agent or Firm:
Sykes Patent Attorney Corporation
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