Title:
ストレプトミセス属細菌のPapMポリペプチドの新規な変異体
Document Type and Number:
Japanese Patent JP4491343
Kind Code:
B2
Abstract:
The present invention relates to novel variants of the PapM polypeptide of bacteria of the Streptomyces genus which possess a substrate selectivity and/or an improved effectiveness compared to the wild-type polypeptide. It also relates to the nucleic acids encoding these variants, to the microorganisms which incorporate these nucleic acids and to their use for producing B components of Streptogramins.
Inventors:
Natalie Bama-Jerk
Denny Thibow
Alan Fametion
Denny Thibow
Alan Fametion
Application Number:
JP2004516853A
Publication Date:
June 30, 2010
Filing Date:
June 23, 2003
Export Citation:
Assignee:
Aventis Pharma Societe Anonym
International Classes:
C07K14/01; C12N15/09; C07K5/02; C12N1/21; C12N9/10; C12N15/54; C12P21/02; C12P21/04; C12Q1/02; C12Q1/48; A61K38/00
Domestic Patent References:
| JP8501696A | ||||
| JP6298664A |
Foreign References:
| WO1996001901A1 |
Other References:
Mol.Microbiol.,Vol.23,No.2(1997)p.191-202
Attorney, Agent or Firm:
Chika Takagi
Junji Yuda
Shoji Miwa
Junji Yuda
Shoji Miwa