Title:
The oligomer biosurfactant in the constituent for skin makeup
Document Type and Number:
Japanese Patent JP6230566
Kind Code:
B2
Abstract:
Oligomeric acylated biosurfactants ("OABs") having low critical micelle concentrations of from about 1.0 ppm to about 200 ppm, preferably less than about 50 ppm, in an aqueous solution of Minimal Essential Media that can lower the surface tension in the aqueous MEM environment to less than about 50 dynes/cm2 and have the ability to increase metabolic soluble proteins and/or increase synthesis of extracellular skin matrix proteins and/or increase rates of cell turnover while at the same time exhibiting comparatively low toxicity-preferably, an LD50 of greater 200 ppm in 37 year-old female fibroblast cells. Another aspect of the present invention is directed to the use of OABs in formulations that are topically-applied, by which is meant the formulation is placed in direct contact with the skin, hair and nails as well as mucosa of the eyes, ears, nose, mouth, anus and vagina.
Inventors:
Owen, Donald
Fan, lili
Fan, lili
Application Number:
JP2015092998A
Publication Date:
November 15, 2017
Filing Date:
April 30, 2015
Export Citation:
Assignee:
Therapeutic Peptides,Inc.
International Classes:
A61K8/64; A61K38/00; A61P17/00; A61P31/04; A61P31/10; A61Q19/00; B01F23/00; C09K23/00
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Foreign References:
| WO2007143006A1 | ||||
| US20070231284 | ||||
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Attorney, Agent or Firm:
Hajime Tsukuni